名稱 | LAG3/NFAT-Luc/Jurkat |
型號(hào) | CBP74060 |
報(bào)價(jià) | ![]() |
特點(diǎn) | LAG3/NFAT-Luc/Jurkat,凍存條件:90% FBS+10% DMSO; |
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聯(lián)系人:蔣經(jīng)理
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74060LAG3/NFAT-Luc/Jurkat

- 詳細(xì)內(nèi)容
CBP74060 | |
I. Background | |
Lymphocyte-activation gene 3 (LAG3, CD223) is a cell surface protein that belongs to immunoglobulin (Ig) superfamily. LAG3 is expressed on activated T cells, natural killer cells, B cells, and plasmacytoid dendritic cells. | |
II. Description | |
Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human LAG3 (lymphocyte-activation gene 3, CD223, GenBank Accession # NM_002286). | |
III. Introduction | |
Host Cell: | Jurkat |
Expressed gene: | NFAT-LAG3-Luciferase |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | LAG3, LAG-3, CD223, Cell Line, Jurkat |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+400ug/ml hygromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
IV. Description of Host Cell Line | |
Organism: | Human |
Tissue: | Peripheral blood |
Disease: | Childhood T acute lymphoblastic leukemia |
Morphology: | Lymphoblast |
Growth Properties: | Suspension |
Ⅴ. Representative Data | |
Figure 1. Recombinant Jurkat stably expressing human LAG3. |
Figure 2. Detect Luciferase assay by Ultra Luciferase Detection Kit CBPH0001(we strongly suggest to purchase from Cobioer). Dose Response of Anti-LAG3 Neutralizing Antibody in LAG3/NFAT Reporter-Jurkat cells. |