| 名稱 | BRAF p.L597V Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10241 |
| 報(bào)價(jià) | 900 |
| 特點(diǎn) | BRAF p.L597V Reference Standard |
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Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10241BRAF p.L597V Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10241 | |
| Format | Genomic DNA |
| Description | BRAF L597V lies within the protein kinase domain of the Braf protein (UniProt.org). L597V results in activation of Braf as indicated by increased phosphorylation of Mek and Erk in cell culture (PMID: 22798288) and and induces cell proliferation and cell viability in culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.1789C>G |
| AA Change | p.L597V |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 33.33% |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM470 |
| Chr position(GRCh37) | chr7:140453146 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
