| 名稱 | CTNNB1 p.D32N Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10249 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | CTNNB1 p.D32N Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10249CTNNB1 p.D32N Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10249 | |
| Format | Genomic DNA |
| Description | CTNNB1 D32N lies within the ubiquitination recognition motif of the Ctnnb1 protein (PMID: 15064718). D32N confers a gain of function on the Ctnnb1 protein as demonstrated by a loss of ubiquitin ligase interaction leading to decreased ubiquitination and increased Ctnnb1-dependent transcription (PMID: 15064718, PMID: 11955436). |
| Technical Data | |
| DNA Change | c.94G>A |
| AA Change | p.D32N |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 32.09% |
| Transcript | ENST00000349496 |
| Cosmic ID | COSM5672 |
| Chr position(GRCh37) | chr3:41266097 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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