www.黄在线看_国产成人午夜精品影院游乐网_国产成人久久av免费高清蜜臀_久久久999久久久_午夜 国产_一区二区三区四区国产

加入收藏 | 設為首頁 | 聯系我們

產品搜索

聯系我們

聯系人:蔣經理
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區緯地路9號
Email: zhangxiangwen@cobioer.com

產品展示 / PRODUCTS
藥靶細胞株 > 腫瘤免疫細胞株 > CBP74163PD-1/OX40 Dual Effector Reporter Cell IO細胞株

PD-1/OX40 Dual Effector Reporter Cell IO細胞株
名稱 PD-1/OX40 Dual Effector Reporter Cell IO細胞株
型號 CBP74163
報價
特點 PD-1/OX40 Dual Effector Reporter Cell
  • 詳細內容
CBP74163
I. Background

The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. The PD-1:PD-L1/2 pathway is also involved in regulating autoimmune responses, making these proteins promising therapeutic targets for a number of cancers, as well as multiple sclerosis, arthritis, lupus, and type I diabetes.

OX40 (CD134) is a co-stimulatory receptor expressed on the surface of CD4+ and CD8+ T cells 24 to 48 hours after activation. Binding of OX40 to its ligand, OX40L (CD252), present on dendritic cells, potentiates T cell survival and increases cytokine production. OX40 has been shown to activate NF-κB-mediated memory cell generation through its interaction with adaptor proteins TRAF2 and TRAF5. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response.

 
II. Introduction
Expressed gene:PD-1/OX40
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin+5ug/ml blasticidin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
 
III. Representative Data

CBP74163 流式1.png

Figure 1. Recombinant PD-1/OX40 Dual Effector Reporter Cell constitutively expressing OX40.

CBP74163 流式2.png

Figure 2. Recombinant PD-1/OX40 Dual Effector Reporter Cell constitutively expressing PD-1.

CBP74163、CBP74164 數據圖.png

Figure 3. Dose Response of Blocking Antibodies in PD-1/OX40 Dual Effector Reporter Cells (C22) With PD-L1 aAPC Cells.

 

如果你對CBP74163PD-1/OX40 Dual Effector Reporter Cell IO細胞株感興趣,想了解更詳細的產品信息,填寫下表直接與廠家聯系:


留言框

  • 產品:

  • 您的單位:

  • 您的姓名:

  • 聯系電話:

  • 常用郵箱:

  • 省份:

  • 詳細地址:

  • 補充說明:

  • 驗證碼:

    請輸入計算結果(填寫阿拉伯數字),如:三加四=7

化工儀器網

推薦收藏該企業網站
主站蜘蛛池模板: 久久国产视屏 | 99re热这里只有精品18 | 成人亚洲精品久久久久 | 超薄丝袜足j好爽在线观看 超黄视频网站 | 中文字幕无码日韩专区免费 | 日本一级毛片免费播 | 国产美女久久久亚洲 | 精品国产免费人成在线观看 | 亚洲精品天天影视综合网 | 久久久久亚洲国产 | 性xxxxx欧美极品少妇 | 国产精品久久久久久久久久日本 | 国产一区在线视频观看 | 亚洲国产精品yw在线观看 | 欧美男生射精高潮视频网站 | 爱爱视频天天看 | 国产绳艺sm调教室论坛 | 极品精品国产超清自在线观看 | 精品无码中出一区二区 | 国产精品国产亚洲区艳妇糸列短篇 | 欧美综合区自拍亚洲综合天堂 | 欧美综合自拍亚洲综合百度 | 99久久综合精品免费 | 一级做a爱过程免费视 | 国产福利片在线 | 国产精品制服 | 自拍偷自拍亚洲精品10p | 国产午夜精品一区二区三区四区 | 欧产日产国产精品 | 四虎视频在线观看 | 成年入口无限观看免费完整大片 | 伊人久久综合成人网小说 | 99久久无色码中文字幕人妻蜜柚 | 亚洲人成网77777色在线播放 | 国产精品无码av一区二区三区 | 成人免费视频88 | 久久精品亚洲99一区二区 | 成人在线观看播放 | 欧美护士激情第一欧美精品 | 亚洲欧美视频网站 | 亚洲人成网站在线播放观看 |